My $.02.
-Ignition coils do fail but rarely.
-To measure low resistance, (below 10 Ohms) you need a very expensive Low Resistance Ohmmeter.
-Buell's use Carbon Suppression wires.
-These break down over time increasing resistance and reducing spark energy.
-IMO these should almost be considered as maintenance items.
-Spiral wires are long lived and tend not to break down as quickly as carbon.
https://www.magnecor.com/magnecor1/truth.htm
As John stated replacing plugs and wires will resolve most ignition issues. Years ago I replaced the stock wires with spiral automotive wires and they've worked great for 40+K on one Buell and 20+K on the other.