I'm running Bridgestone S22's on my S1. For the amount and type of riding I do, I'd rather have a tire that is more likely to forgive me if I go a little too hot into a turn, rather than squeak out as many miles as possible. Plus, my tires are more likely to go bad from dry rot than high mileage anyhow.
Captain Cheapskate (aka CoOter) should have some better advice on tires as he actually rides his motorcycle.